Protein Details: TWiK family of potassium channels protein 18

Protein ID

ICDB_Pro_0854

Protein Name

TWiK family of potassium channels protein 18

Gene Name

twk-18; C24A3.6

Organism

Caenorhabditis elegans

Length

461 amino acids

AlphaFoldDB

AF-Q18120-F1-model_v4.pdb

Function

Sequence

MAIVAQGVSTILTTFQKTFKGLLPLIILVAYTLLGAWIFWMIEGENEREMLIEQQKERDELIRRTVYKINQLQIKRQRRLMTAEEEYNRTAKVLTTFQETLGIVPADMDKDIHWTFLGSIFYCMTVYTTIGYGNIVPGTGWGRFATILYAFIGIPLTVLSLYCLGSLFAKGCKMLWRFFLKSTRVVSKDLSNKISEAADNIEEGTTAITPSAEKTENNDDDLLSFPISGLLLITVIWVIFCAVLFTFLEEWDFGTSLYFTLISFTTIGFGDILPSDYDFMPIVGVLLLIGLSLVSTVMTLIQQQIEALASGMKDNIDQEYARALNEAREDGEVDEHVDPEEDPENNKKSFDAVISRMNWSKRGLYYLLPDSQKKELAKQSEKKMGRKSIKIQTDNDLLETLIREEILKAELNNEMHKYTAPRSSHQPKLVYSDVREKEVPIEVVRVEHFNHGNEDYLEHDI

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Expressed in body wall muscle.

DOI ID

10.1523/jneurosci.20-20-07517.2000; 10.1126/science.282.5396.2012; 10.1074/mcp.m600392-mcp200

RefSeq

NP_509516.1